尹晓敏

发布时间:2023-07-21录入员:

 

姓名:尹晓敏

职称:副教授

个人简介:江苏南通人,医学博士。

专业研究领域:神经退行性疾病的机制研究。

专著与论集:

1. Yin X, Li Y, Fan X, Huang F, Qiu Y, Zhao C, Zhou Z, Gu Q, Xia L, Bao J, Wang X, Liu F, Qian W. SIRT1 deficiency increases O-GlcNAcylation of tau, mediating synaptic tauopathy. Mol Psychiatry. 2022;27(10):4323-4334.

2. Yin X, Zhao C, Qiu Y, Zhou Z, Bao J, Qian W. Dendritic/Post-synaptic Tau and Early Pathology of Alzheimer's Disease. Front Mol Neurosci. 2021;14:671779.

3. Yin X, Zhou Z, Qiu Y, et al. SIRT1 Regulates Tau Expression and Tau Synaptic Pathology. J Alzheimers Dis. 2021;84(2):895-904.

4. Yin X, Jiang X, Wang J, et al. SIRT1 Deacetylates SC35 and Suppresses Its Function in Tau Exon 10 Inclusion. J Alzheimers Dis. 2018;61(2):561-570.

5. Yin X, Jin N, Shi J, et al. Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice. Sci Rep. 2017;7(1):619.

6. Yin X, Jin N, Gu J, et al. Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusion. J Biol Chem. 2012;287(36):30497-30506.

主要科研项目

主持国家自然科学基金项目1项,江苏省高校自然科学基金1项。

讲授课程

生物化学与分子生物学

指导研究生情况